Connect
Mosaic is an MCP server: the tools land inside Claude, next to where the question was asked. Connecting is free and takes about a minute.
In Claude
- 1In claude.ai (or the Claude desktop app), open Settings → Connectors → Add custom connector.
- 2Paste the connector URL:
https://mcp.getmosaic.dev/mcp - 3Sign in with your email — we send a one-time link, you approve the connection, and the tools appear in your next chat. No password, no API key to paste.
Then ask Claude: “show me the Mosaic coverage grid for PCSK9”
Self-host
The server is open source. Run it locally with uvx mosaic-mcp — bring your own Postgres: the package ships the query layer and schema, not a shared database. Source and setup at github.com/sourabhnk/mosaic-mcp.
The tools
Free — 50 queries / month
mosaic_get_target_profile
Full profile for a curated target — biology, scores, structure, SAR, pipeline, every count with its state.
mosaic_get_target_compounds
Chemistry for a curated target, filterable, with potency and clinical phase.
mosaic_get_target_papers
Literature under the declared PubMed query, with validation classification.
mosaic_get_target_structure
AlphaFold structure, confidence and pocket druggability.
mosaic_get_coverage_grid
The coverage grid for ANY human gene symbol — what's known, what's a floor, what nobody has checked.
Pro — everything above, plus
mosaic_request_dossier
Queue a coverage-honest dossier for any human target; async, delivered in-session and by email.
mosaic_get_dossier
Poll a request; returns the full document when delivered, the stated failure cause when not.
mosaic_pathway_context
Reactome pathway membership and neighbours.
mosaic_target_validation
Genetic, in-vivo and clinical validation evidence, classified and counted.
mosaic_clinical_pipeline
Compounds in the clinic for a target, by phase and indication.
mosaic_synthetic_lethal_whitespace
Co-essentiality partners with sparse chemistry — stated as floors, never as absence.
mosaic_resistance_bypass_map
Bypass-signalling candidates around a target from the interaction layer.
mosaic_target_network
The local interaction network with confidence scores.
Plans and dossier quotas are on the pricing section →